Physiology

Image-guided therapy

iFR

Be confident in treatment and deferral decisions with Philips iFR.

 
iFR is in a class of its own and is the leading hyperemia-free physiologic index for measuring pressure in diagnostic and interventional procedures. Only offered by Philips, iFR Co-registration maps the physiologic measurements directly onto the angiogram enabling more complete procedural guidance. No other resting index has an ESC and ACC/AHA/SCAI Class IA recommendation based on the high level of clinical evidence for its accuracy. Philips iFR is the Gold Standard 1,2

Demonstrated results

1 in 4


Patients with angiographically successful PCI left the cath lab with residual ischemia (defined as iFR <0.90 residual DS < 50% in any treated lesion).
3

68%


Relative reduction in clinical events at one year. follow-up among patients achieving post-PCI iFR ≥ 0.95 (p-value=0.04).
4

81.6%


Of the patients with residual ischemia were caused by an untreated angiographically inapparent physiologically focal stenosis (≤ 15 mm).
3

$1024


On average saved with iFR compared to FFR, as found by iFR Swedeheart.
5

Features

iFR Co-registration

Only iFR has co-registration for advanced physiologic guidance


Map iFR values directly onto the angiogram so you can see which parts of a vessel are causing ischemia. With iFR Co-registration there is no need for hyperemic drugs. You can automatically co-register values in seconds onto the angiogram.
 

  • Better discern focal, serial or diffuse disease6
  • Determine precise lesion severity and location7,8
  • Make length measurements without a cumbersome pullback device6
  • Estimate the physiologic impact of a virtual stent6
     

iFR co registration is available on the new Philips IntraSight interventional applications platform and as an upgrade to the Core systems.

iFR pullback technology

iFR pullback technology7


iFR pullback technology reveals the physiologic profile of the entire vessel, so when you encounter diffuse disease or serial lesions you can make informed treatment decisions.

 

•  Provides beat-by-beat iFR pressure measurements across the entire vessel, artery-by-artery

•  Establishes the physiological significance of each vessel and/or individual lesion (focal or diffuse)

•  Provides a clear view of the functional gain

Image gallery

Philips Omniwire

Featured product

iFR technology is available on

  •  

    IntraSight  

    The IntraSight applications platform is where imaging, physiology, co-registration* and software all come together to clearly identify coronary and peripheral artery disease, and allow for more optimized treatment plans. IntraSight is built on a new foundational platform designed to meet the evolving needs of your lab today and tomorrow.

    IGTDINTRSGHT
  •  

    SyncVision  

    The SyncVision precision guidance system is suitable with IntraSight and Core Integrated interventional platforms and streamlines lesion assessment, simplifies vessel sizing and enables precise therapy delivery all while integrating seamlessly in daily workflows in interventional suites of choice.

Class IA recommendation award

Class IA recommendation


Only Philips iFR has a Class IA recommendation by the ACC/AHA/SCAI and ESC1,2

Documentation

Resources
Clinical articles
Video assets

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Footnotes
 

[1] Neumann, F-J et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. European Heart Journal (2019) 40, 87–165.
[2] Lawton J. et al. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization. JACC. 2022;79(2):e21-e129.
[3] Jeremias A et al. Blinded physiological assessment of residual ischemia after successful angiographic percutaneous coronary Intervention: The DEFINE PCI Study. JACC Cardiovasc Interv. 2019 Oct 28;12(20):1991-2001.
[4] Patel et al. 1-Year Outcomes of Blinded Physiological Assessment of Residual Ischemia After Successful PCI. J Am Coll Cardiol Intv 2022;15:52–6.
[5] Berntorp et al. Instantaneous wave-free ratio compared with fractional flow reserve in PCI: A cost-minimization analysis. Int J Cardiol 2021 1;344:54-59.
[6] Nijjer SS, et al. Pre-angioplasty instantaneous wave-free ratio pullback provides virtual intervention and predicts hemodynamic outcome for serial lesions and diffuse coronary re-angioplasty instantaneous wave-free ratio pullback provides virtual intervention and predicts hemodynamic outcome for serial lesions and diffuse coronary artery disease. JACC Cardiovasc Interv. 2014;7(12):1386-96.
[7] Co-registration operator's manual D001336104_A_300010660481
[8] Data on file at Philips Syncvision co-registration validation report D001370468_B
[9] Davies JE, et al., Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI. N Engl J Med. 2017 24-1834
[10] Gotberg M, et al. iFR-SWEDEHEART Investigators. Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI. N Engl J Med. 2017 May 11;376(19):1813-1823.
[11] Data on file at Philips D000410086_A, D000485394_A

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