Helps reduce the risk of inhaler side effects1, 2, 3, 4, 5, 6, 7.
Aerosol medicine comes out of the inhaler very quickly so it is often very difficult to use an inhaler correctly because the canister needs to be pressed at the same time as you breathe in8, 9.
Enhances your treatment. Medicine often ends up in your mouth, throat and stomach when using an inhaler on its own. A valved holding chamber may improve drug delivery to the lungs where it is needed by as much as up to 4 times10.
Babies and all young children, who cannot use the mouthpiece of the chamber, should be encouraged to use a facemask11, 12. It is important that the facemask fits comfortably on the face, providing a good fit, to help them receive the proper dose of inhaler medication.
To use the mouthpiece effectively your child needs to be able to firmly close their teeth and lips around the mouthpiece so they can take a slow deep breath and hold the breath for a few seconds. Children who cannot do this, will need to use a facemask.
FOOTNOTES:
[1] Salzman G., Pyszynski D. Oropharyngeal candidiasis in patients treated with beclomethasone dipropionate delivered by metered-dose inhaler along and with Aerochamber. Journal of Allergy and Clinical Immunology, 1988; Volume 81, Issue 2: 424-428.
[2] Derendorf H., Nave R., Drollmann A., Cerasoli F., Wurst W. Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma. European Respiratory Journal, 2006; 28:1042-1050.
[3] Roller M., Zhang G., Troedson R.G., Leach C.L., Le Souëf P.N., Devadason S.G. Spacer inhaler technique and deposition of extra fine aerosol in asthmatic children. European Respiratory Journal, 2007; 29:299-306.
[4] Von Hollen D., Slater L., Hatley RHM. Impact of flow rate on NGI throat deposition from 3 HFA Inhaler formulations with anti-static valved holding chambers. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2013; 26(2); A45-A46.
[5] Oliveira R.F., et al. VHC performance evaluation at constant flow: 30L/min. Proceedings of the ASME2015 International Mechanical Engineering Congress and Exposition, 2015 Houston Texas.
[6] Leach C., Colice G. A Pilot Study to Assess Lung Deposition of HFA-Beclomethasone and CFC-Beclomethasone from a pressurized Metered Dose Inhaler with and without add-on spacers and using varying breath hold times. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2010; 23(6):355-361.
[7] Dickens G., et al. Pharmacokinetics of flunisolide administered via metered dose inhaler with and without a spacer device and following oral administration. Annals of Allergy, Asthma & Immunology, 2000; Volume 84, 528-532.
[8] Saunders K.B. Misuse of inhaled bronchodilator agents. Br Med J. 1965; 1:1037-1038.
[9] Oprehek J., et al. Patient error in use of bronchodilator metered aerosols. Br Med J. 1976; 1:76.
[10] Gardenhire D., Arzu A., Dean H., Myers T. A guide to aerosol delivery devices for respiratory therapists 3rd edition, American Association for Respiratory Care, 2013.
[11] Nhlbi.nih.gov. Delivery devices in infants and young children. Accessed September 2017.
[12] Hsu W., et al. Evaluation of delivery efficiency from valved holding chambers with facemasks. Resp. Drug Delivery Europe, 2011; 2:505-510.
[13] Lung.org. Managing asthma/Valved holding chambers. Accessed September 2017.
[14] Everard ML., Clark AR., Milner AD. Drug delivery from holding chamber with facemask. Arch Dis Child, 1992; 67:580-585.
[15] Mitchell J. et al. Electrostatic and inhaled medications: Influence on delivery via pressurized metered dose inhalers and add on devices. Respiratory Care, 2000. Volume 52(3):283-300.
[16] Adapted from: Hirst, PH., et al. Deposition and pharmacokinetics of an HFA formulation of Triamcinolone Acetonide delivered by pressurized metered dose inhaler. Journal of Aerosol Medicine. 2001; Volume 14 (2):155-166.
[17] Adapted from Erzinger, S. et al. Facemaks and aerosol delivery in vivo. Journal Aerosol Medicine 2007; 20 (Suppl 1):S78-S84
[18] Among retail pharmacies who claim to have a preferred brand of spacer in their pharmacy. Online survey conducted on 205 registered retail pharmacists.